Smarcc2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Smarcc2
SWI/SNF related BAF chromatin remodeling complex subunit C2
MGI:1915344

20 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Emx1^tm1(cre)Krj/Emx1⁺ Tg(CMV-GFP,-Smarcc2,-lacZ)#Stoy/0 involves: 129S2/SvPas	abnormal DNA methylation	J:197141
	abnormal neocortex morphology	J:197141
	abnormal neuron differentiation	J:197141
	abnormal neuron number	J:197141
	abnormal neuronal precursor cell number	J:197141
	thin cerebral cortex	J:197141
Smarcc2^em1(IMPC)J/Smarcc2⁺ C57BL/6NJ-Smarcc2^em1(IMPC)J/Mmjax	abnormal auditory brainstem response	J:211773
	decreased heart rate	J:211773
	decreased thigmotaxis	J:211773
	increased mean corpuscular volume	J:211773
	prolonged RR interval	J:211773
Smarcc2^em1(IMPC)J/Smarcc2^em1(IMPC)J C57BL/6NJ-Smarcc2^em1(IMPC)J/Mmjax	preweaning lethality, complete penetrance	J:211773
Smarcc2^tm1.1Grc/Smarcc2^tm1.1Grc involves: 129S6/SvEvTac * C57BL/6	postnatal lethality	J:101977
Smarcc2^tm1.1Stoy/Smarcc2^tm1.1Stoy involves: 129S1/Sv * C57BL/6	no abnormal phenotype detected	J:197141
Smarcc2^tm1.1Stoy/Smarcc2^tm1.1Stoy involves: 129S1/Sv * C57BL/6	abnormal neuronal precursor proliferation	J:197141
Smarcc2^tm1.1Stoy/Smarcc2^tm1.1Stoy Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S1/Sv * 129S2/SvPas * C57BL/6	abnormal DNA methylation	J:197141
	abnormal neocortex morphology	J:197141
	abnormal neuron differentiation	J:197141
	abnormal neuronal precursor cell number	J:197141
	abnormal neuronal precursor proliferation	J:197141
	thickened cerebral cortex	J:197141
Smarcc2^tm1.1Stoy/Smarcc2^tm1.1Stoy Neurod6^tm1(cre)Kan/Neurod6⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal nervous system phenotype	J:197141
Smarcc2^tm1.2Stoy/Smarcc2^tm1.2Stoy involves: 129S1/Sv * BALB/cJ * C57BL/6	increased embryo weight	J:197141
	neonatal lethality, incomplete penetrance	J:197141
	postnatal lethality, complete penetrance	J:197141

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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