44 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+ Kat8tm1Thl/Kat8+ involves: 129S1/Sv	abnormal DNA repair	J:128936
	decreased fibroblast proliferation	J:128936
	increased cellular sensitivity to ionizing radiation	J:128936
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+ Kat8tm1Thl/Kat8tm1Thl involves: 129S1/Sv	decreased fibroblast proliferation	J:128936
Kat8em1(IMPC)Mbp/Kat8+ C57BL/6N-Kat8em1(IMPC)Mbp/MbpMmucd	abnormal behavior	J:211773
	abnormal kidney morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal lymph node morphology	J:211773
	blind uterus	J:211773
	decreased locomotor activity	J:211773
	decreased thigmotaxis	J:211773
	enlarged lymph nodes	J:211773
	increased circulating cholesterol level	J:211773
	small heart	J:211773
Kat8em1(IMPC)Mbp/Kat8em1(IMPC)Mbp C57BL/6N-Kat8em1(IMPC)Mbp/MbpMmucd	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Kat8tm1.1Avo/Kat8tm1.1Avo involves: BALB/cJ * C57BL/6	abnormal chromosome morphology	J:139761
	abnormal inner cell mass apoptosis	J:139761
	absent inner cell mass proliferation	J:139761
	decreased trophectoderm cell proliferation	J:139761
	embryonic lethality between implantation and somite formation, complete penetrance	J:139761
	increased mitotic index	J:139761
Kat8tm1.2Avo/Kat8tm1.2Avo Tg(Nes-cre)1Kln/0 involves: C57BL/6 * SJL	abnormal brain vasculature morphology	J:291094
	abnormal cerebral cortex morphology	J:291094
	abnormal embryonic/fetal subventricular zone morphology	J:291094
	abnormal pericyte morphology	J:291094
	enlarged lateral ventricles	J:291094
	hemorrhage	J:291094
	increased fatty acids level	J:291094
	lethality during fetal growth through weaning, incomplete penetrance	J:291094
	postnatal lethality, complete penetrance	J:291094
Kat8tm1Thl/Kat8tm1Thl Amhr2tm3(cre)Bhr/Amhr2+ involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6	normal reproductive system phenotype	J:242000
Kat8tm1Thl/Kat8tm1Thl Tg(Gdf9-icre)5092Coo/0 involves: 129S1/Sv * C57BL/6	abnormal epigenetic regulation of gene expression	J:242000
	abnormal female germ cell physiology	J:242000
	abnormal oocyte morphology	J:242000
	abnormal oogenesis	J:242000
	decreased oocyte number	J:242000
	decreased ovary weight	J:242000
	female infertility	J:242000
	impaired ovarian folliculogenesis	J:242000
	increased atretic ovarian follicle number	J:242000
	increased female germ cell apoptosis	J:242000
	oxidative stress	J:242000
	small ovary	J:242000
Kat8tm2Thl/Kat8tm2Thl involves: 129S1/Sv	abnormal embryo development	J:128936
	embryonic lethality between implantation and somite formation, complete penetrance	J:128936