Ufl1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ufl1
UFM1 specific ligase 1
MGI:1914740

23 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ufl1^{tm1a(EUCOMM)Wtsi}/Ufl1⁺ C57BL/6N-Ufl1^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased body weight	J:175295
	decreased circulating alanine transaminase level	J:175295
	decreased circulating aspartate transaminase level	J:175295
	decreased total body fat amount	J:175295
Ufl1^{tm1a(EUCOMM)Wtsi}/Ufl1^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	anemia	J:238253
	decreased embryo size	J:238253
	decreased erythroid progenitor cell number	J:238253
	embryonic lethality during organogenesis, complete penetrance	J:238253
	increased nucleated erythrocyte cell number	J:238253
	small liver	J:238253
Ufl1^{tm1c(EUCOMM)Wtsi}/Ufl1^{tm1c(EUCOMM)Wtsi} Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor⁺ involves: 129S4/SvJae * C3H * C57BL/6 * C57BL/6N	abnormal autophagy	J:238253
	abnormal bone marrow cell physiology	J:238253
	anemia	J:238253
	decreased erythrocyte cell number	J:238253
	decreased erythroid progenitor cell number	J:238253
	decreased granulocyte number	J:238253
	decreased hematocrit	J:238253
	decreased hemoglobin content	J:238253
	decreased leukocyte cell number	J:238253
	decreased lymphocyte cell number	J:238253
	decreased monocyte cell number	J:238253
	pancytopenia	J:238253
	premature death	J:238253
	thrombocytopenia	J:238253
	weight loss	J:238253

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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