Rnpc3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rnpc3
RNA-binding region (RNP1, RRM) containing 3
MGI:1914475

37 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/Ndor1⁺ Rnpc3^{tm1c(EUCOMM)Wtsi}/Rnpc3⁺ involves: 129S/SvEv * C57BL/6 * C57BL/6N	no abnormal phenotype detected	J:267519
Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/Ndor1⁺ Rnpc3^{tm1c(EUCOMM)Wtsi}/Rnpc3^{tm1c(EUCOMM)Wtsi} involves: 129S/SvEv * C57BL/6 * C57BL/6N	abnormal digestive system morphology	J:267519
	abnormal enterocyte proliferation	J:267519
	abnormal esophageal squamous epithelium morphology	J:267519
	abnormal intestinal epithelium morphology	J:267519
	abnormal intestinal mucosa morphology	J:267519
	abnormal large intestine crypts of Lieberkuhn morphology	J:267519
	abnormal skin morphology	J:267519
	abnormal small intestinal crypt cell proliferation	J:267519
	abnormal small intestine crypts of Lieberkuhn morphology	J:267519
	abnormal stomach glandular epithelium morphology	J:267519
	anemia	J:267519
	decreased erythrocyte cell number	J:267519
	decreased leukocyte cell number	J:267519
	decreased lymphocyte cell number	J:267519
	decreased monocyte cell number	J:267519
	decreased small intestinal villus height	J:267519
	decreased thymus weight	J:267519
	disheveled coat	J:267519
	epidermal atrophy	J:267519
	esophageal inflammation	J:267519
	hunched posture	J:267519
	increased small intestinal crypt cell apoptosis	J:267519
	moribund	J:267519
	sebaceous gland atrophy	J:267519
	small intestinal inflammation	J:267519
	thrombocytopenia	J:267519
	thymus atrophy	J:267519
	thymus cortex atrophy	J:267519
	thymus medulla atrophy	J:267519
	weight loss	J:267519
Rnpc3^em1(IMPC)H/Rnpc3^em1(IMPC)H C57BL/6NTac-Rnpc3^em1(IMPC)H/H	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Rnpc3^{tm1a(EUCOMM)Wtsi}/Rnpc3⁺ involves: C57BL/6N	no abnormal phenotype detected	J:267519
Rnpc3^{tm1b(EUCOMM)Wtsi}/Rnpc3⁺ involves: C57BL/6N	no abnormal phenotype detected	J:267519
Rnpc3^{tm1b(EUCOMM)Wtsi}/Rnpc3^{tm1b(EUCOMM)Wtsi} involves: C57BL/6N	embryonic lethality before implantation, complete penetrance	J:267519
Rnpc3^{tm1b(EUCOMM)Wtsi}/Rnpc3^{tm1b(EUCOMM)Wtsi} involves: C57BL/6N * FVB	abnormal preimplantation embryo development	J:267519
	embryonic growth arrest	J:267519
	failure of blastocyst to hatch from the zona pellucida	J:267519

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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