40 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mmachcem1.1Poche/Mmachcem1.1Poche involves: C57BL/6J * FVB/N	abnormal craniofacial morphology	J:297666
	abnormal embryo turning	J:297666
	anophthalmia	J:297666
	decreased fetal size	J:297666
	heart right ventricle hypoplasia	J:297666
	lethality throughout fetal growth and development, complete penetrance	J:297666
Mmachcem1Poche/Mmachcem1Poche E2f1Tg(Wnt1-cre)2Sor/E2f1+ involves: 129S4/SvJae * C3H * C57BL/6 * C57BL/6J	normal craniofacial phenotype	J:317822
MmachcGt(AZ0348)Wtsi/Mmachc+ involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6	abnormal metabolism	J:212387
	increased circulating homocysteine level	J:212387
	transmission ratio distortion	J:212387
MmachcGt(AZ0348)Wtsi/Mmachc+ involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * CD-1	normal reproductive system phenotype	J:212387
MmachcGt(AZ0348)Wtsi/MmachcGt(AZ0348)Wtsi involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6	abnormal blastocyst formation	J:212387
	decreased trophectoderm cell proliferation	J:212387
	embryonic lethality before implantation, complete penetrance	J:212387
	failure of blastocyst to hatch from the zona pellucida	J:212387
	impaired embryo implantation	J:212387
MmachcGt(AZ0348)Wtsi/MmachcGt(AZ0348)Wtsi involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * CD-1	embryonic lethality before implantation, complete penetrance	J:212387
	impaired embryo implantation	J:212387
Mmachctm1.1(NCOM)Mfgc/Mmachc+ C57BL/6N-Mmachctm1.1(NCOM)Mfgc/Tcp	abnormal epididymis morphology	J:211773
	abnormal lung morphology	J:211773
	enlarged lymph nodes	J:211773
	small kidney	J:211773
Mmachctm1.1(NCOM)Mfgc/Mmachctm1.1(NCOM)Mfgc C57BL/6N-Mmachctm1.1(NCOM)Mfgc/Tcp	abnormal craniofacial morphology	J:211773, J:297666
	abnormal embryo size	J:211773
	abnormal embryo turning	J:297666
	abnormal eye morphology	J:211773
	abnormal heart ventricle morphology	J:297666
	abnormal palatal shelf fusion at midline	J:297666
	abnormal spinal cord morphology	J:297666
	anophthalmia	J:211773, J:297666
	decreased embryo size	J:297666
	decreased fetal size	J:297666
	edema	J:211773
	exencephaly	J:297666
	facial cleft	J:211773, J:297666
	lethality throughout fetal growth and development, complete penetrance	J:297666
	microphthalmia	J:211773, J:297666
	pallor	J:211773
	polydactyly	J:211773
	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	ventricular septal defect	J:297666
Mmachctm1.1(NCOM)Mfgc/Mmachctm1.1(NCOM)Mfgc Tg(CAG-Mmachc,-GFP)1Poche/0 C57BL/6-Mmachctm1.1(NCOM)Mfgc Tg(CAG-Mmachc,-GFP)1Poche	normal craniofacial phenotype	J:297666
	decreased body size	J:297666
	increased circulating homocysteine level	J:297666
	increased circulating methylmalonic acid level	J:297666
	normal nervous system phenotype	J:297666
	normal vision/eye phenotype	J:297666
Tg(CAG-Mmachc,-GFP)1Poche/0 C57BL/6J-Tg(CAG-Mmachc,-GFP)1Poche	no abnormal phenotype detected	J:297666