Med28 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Med28
mediator complex subunit 28
MGI:1914249

17 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Med28^{tm1.1(KOMP)Vlcg}/Med28⁺ C57BL/6N-Med28^{tm1.1(KOMP)Vlcg}/MbpMmucd	abnormal embryo size	J:211773
Med28^{tm1.1(KOMP)Vlcg}/Med28⁺ C57BL/6N-Med28^{tm1.1(KOMP)Vlcg}/Ucd	abnormal auditory brainstem response	J:211773
	abnormal spleen morphology	J:211773
	decreased circulating serum albumin level	J:211773
	increased body length	J:211773
	increased respiratory quotient	J:211773
	small spleen	J:211773
Med28^{tm1.1(KOMP)Vlcg}/Med28^{tm1.1(KOMP)Vlcg} C57BL/6N-Med28^{tm1.1(KOMP)Vlcg}/MbpMmucd	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
Med28^{tm1.1(KOMP)Vlcg}/Med28^{tm1.1(KOMP)Vlcg} C57BL/6N-Med28^{tm1.1(KOMP)Vlcg}/Ucd	preweaning lethality, complete penetrance	J:211773
Med28^tm1.1Vra/Med28⁺ involves: 129S4/SvJae * C57BL/6	abnormal pluripotent precursor cell morphology	J:243694
Med28^tm1.1Vra/Med28^tm1.1Vra involves: 129S4/SvJae * C57BL/6	abnormal pluripotent precursor cell morphology	J:243694
Med28^tm1.2Vra/Med28^tm1.2Vra involves: 129S4/SvJae * C57BL/6	abnormal blastocyst morphology	J:243694
	absent egg cylinders	J:243694
	absent embryonic epiblast	J:243694
	absent inner cell mass proliferation	J:243694
	disorganized extraembryonic tissue	J:243694
	embryonic lethality at implantation, complete penetrance	J:243694

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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