Lpin1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lpin1
lipin 1
MGI:1891340

24 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lpin1²⁰⁸⁸⁴/Lpin1²⁰⁸⁸⁴ involves: C57BL/6J	abnormal action potential	J:153042
	abnormal gait	J:153042
	abnormal myelin sheath morphology	J:153042
	abnormal sciatic nerve morphology	J:153042
	decreased joint mobility	J:153042
	decreased nerve conduction velocity	J:153042
	demyelination	J:153042
	increased grip strength	J:153042
Lpin1^fld-2J/Lpin1^fld-2J C3H/HeJ-Lpin1^fld-2J/J	abnormal fat cell morphology	J:66739
	abnormal gait	J:66739
	decreased body fat mass	J:66739
	decreased brown adipose tissue mass	J:66739
	decreased brown fat cell lipid droplet size	J:66739
	decreased circulating leptin level	J:66739
	decreased white adipose tissue mass	J:66739
	decreased white fat cell lipid droplet size	J:66739
	enlarged liver	J:66739
	hepatic steatosis	J:66739
	insulin resistance	J:66739
	male infertility	J:66739
	peripheral nervous system degeneration	J:66739
	tremors	J:66739
Lpin1^tm1Rchr/Lpin1^tm1Rchr Tg(Mpz-cre)26Mes/0 involves: 129S6/SvEvTac * FVB/N	abnormal action potential	J:137213
	abnormal gait	J:137213
	abnormal nervous system electrophysiology	J:137213
	abnormal Schwann cell morphology	J:137213
	abnormal sciatic nerve morphology	J:137213
	decreased nerve conduction velocity	J:137213
	demyelination	J:137213
	limb grasping	J:137213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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