54 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Efemp2tm1.1Chu/Efemp2+ B6(SJL)-Efemp2tm1.1Chu	increased aorta wall thickness	J:223792
Efemp2tm1.1Chu/Efemp2tm1.1Chu B6(SJL)-Efemp2tm1.1Chu	abnormal aorta elastic tissue morphology	J:223792
	abnormal aorta smooth muscle morphology	J:223792
	abnormal ascending aorta morphology	J:223792
	abnormal cutaneous collagen fibril morphology	J:223792
	abnormal cutaneous elastic fiber morphology	J:223792
	abnormal descending aorta morphology	J:223792
	abnormal forelimb morphology	J:223792
	abnormal hypodermis muscle layer morphology	J:223792
	abnormal tendon collagen fibril morphology	J:223792
	alopecia	J:223792
	ascending aorta aneurysm	J:223792
	blepharoptosis	J:223792
	dilated aorta bulb	J:223792
	enlarged heart	J:223792
	focal dorsal hair loss	J:223792
	increased aorta wall thickness	J:223792
	increased artery tortuosity	J:223792
	increased carotid artery tortuosity	J:223792
	loose skin	J:223792
	overexpanded pulmonary alveolus	J:223792
	respiratory distress	J:223792
	thin dermal layer	J:223792
	wheezing	J:223792
Efemp2tm1.1Hiya/Efemp2tm1.2Hiya Tg(Tagln-cre)1Her/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal aorta elastic fiber morphology	J:170883
	abnormal aorta smooth muscle morphology	J:213282
	abnormal aorta tunica media morphology	J:170883
	abnormal aorta wall morphology	J:213282
	abnormal ascending aorta morphology	J:170883, J:213282
	abnormal blood vessel physiology	J:213282
	abnormal vascular smooth muscle morphology	J:170883
	ascending aorta aneurysm	J:170883, J:213282
	decreased systemic arterial diastolic blood pressure	J:213282
	dilated ascending aorta	J:213282
	increased pulse pressure	J:213282
	premature death	J:170883
Efemp2tm1.1Hiya/Efemp2tm1.2Hiya Tg(Tek-cre)1Ywa/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	no abnormal phenotype detected	J:170883
Efemp2tm1.1Tynk/Efemp2tm1.1Tynk Tg(Tagln-cre)1Her/0 involves: C57BL/6 * SJL	abnormal aorta elastic tissue morphology	J:154659
	abnormal blood vessel physiology	J:154659
Efemp2tm1.1Tynk/Efemp2tm1.2Tynk Tg(Tagln-cre)1Her/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal aorta elastic tissue morphology	J:154659
	abnormal aortic arch morphology	J:154659
	abnormal blood vessel physiology	J:154659
	aortic valve regurgitation	J:154659
	ascending aorta aneurysm	J:154659
	dilated ascending aorta	J:154659
	heart left ventricle hypertrophy	J:154659
Efemp2tm1.2Hiya/Efemp2tm1.2Hiya involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal aorta elastic fiber morphology	J:170883
	abnormal aorta tunica media morphology	J:170883
	abnormal vascular smooth muscle morphology	J:170883
	abnormal vascular smooth muscle physiology	J:170883
	ascending aorta aneurysm	J:170883
	increased vascular endothelial cell apoptosis	J:170883
	increased vascular endothelial cell proliferation	J:170883
	increased vascular smooth muscle cell proliferation	J:170883
	perinatal lethality, complete penetrance	J:170883
	vascular smooth muscle hyperplasia	J:170883
Efemp2tm1.2Tynk/Efemp2tm1.2Tynk involves: C57BL/6	abnormal aorta elastic tissue morphology	J:154659
	abnormal aorta morphology	J:154659
	diaphragmatic hernia	J:154659
	neonatal lethality, complete penetrance	J:154659
Efemp2tm1Dgen/Efemp2+ involves: 129P2/OlaHsd * C57BL/6	abnormal aorta tunica media morphology	J:129341
	no abnormal phenotype detected	J:101679
Efemp2tm1Dgen/Efemp2tm1Dgen involves: 129P2/OlaHsd * C57BL/6	abnormal aorta elastic tissue morphology	J:106902, J:154659
	abnormal aorta morphology	J:106902
	abnormal aorta smooth muscle morphology	J:106902
	abnormal aorta wall morphology	J:106902
	abnormal artery morphology	J:106902
	abnormal hypodermis morphology	J:106902
	abnormal pulmonary elastic fiber morphology	J:106902
	aneurysm	J:154659
	artery stenosis	J:106902
	descending aorta stenosis	J:106902
	embryonic lethality during organogenesis, complete penetrance	J:101679
	emphysema	J:106902
	hemorrhage	J:106902
	increased aorta wall thickness	J:106902
	perinatal lethality, complete penetrance	J:106902