Tbc1d1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tbc1d1
TBC1 domain family, member 1
MGI:1889508

15 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tbc1d1^{Gt(E140H06)Wrst}/Tbc1d1^{Gt(E140H06)Wrst} B6.129P2-Tbc1d1^{Gt(E140H06)Wrst}	abnormal homeostasis	J:203285
	abnormal lipid oxidation	J:203285
	abnormal muscle cell glucose uptake	J:203285
	decreased body weight	J:203285
	decreased lean body mass	J:203285
	decreased respiratory quotient	J:203285
	decreased susceptibility to diet-induced obesity	J:203285
	decreased total body fat amount	J:203285
	normal homeostasis/metabolism phenotype	J:203285
	increased basal metabolism	J:203285
	increased fatty acid oxidation	J:203285
Tbc1d1^{Nobq1-NZO/HlBom}/? involves: NZO/HlBom * SJL/NBom	increased circulating insulin level	J:66744
Tbc1d1^{Nobq1-NZO/HlBom}/? involves: NZO/HlBom * SJL/NBom	increased white adipose tissue amount	J:66744
Tbc1d1^{Nobq1-SJL/NBom}/Tbc1d1^{Nobq1-SJL/NBom} B6.SJL-(D5Mit302-D5Mit307)	decreased circulating glucose level	J:143559
	decreased susceptibility to diet-induced obesity	J:143559
	decreased total body fat amount	J:143559
Tbc1d1^tm1.1Schen/Tbc1d1^tm1.1Schen involves: C57BL/6 * CBA	no abnormal phenotype detected	J:186867

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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