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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Icmt
isoprenylcysteine carboxyl methyltransferase
MGI:1888594
19 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Icmttm1Hzo/Icmttm1Hzo
involves: 129S/SvEv 		abnormal definitive hematopoiesis J:77742
abnormal liver bud morphology J:77742
abnormal liver development J:77742
absent liver J:77742
decreased embryo size J:77742
delayed hepatic development J:77742
embryonic lethality during organogenesis, complete penetrance J:77742
increased forebrain apoptosis J:77742
increased neural tube apoptosis J:77742
pallor J:77742
Icmttm1Mbrg/Icmttm1Mbrg
involves: 129S4/SvJae 		no abnormal phenotype detected J:88170
Icmttm1Mbrg/Icmttm1Mbrg
Tg(Mx1-cre)1Cgn/?
involves: 129S4/SvJae * C57BL/6 * CBA 		decreased cell proliferation J:88170
Icmttm1Mbrg/Icmttm1Mbrg
Tg(Six3-cre)69Frty/0
involves: 129 * C57BL/6 * DBA/2 		abnormal electroretinogram waveform feature J:231728
abnormal retina neuronal layer morphology J:231728
abnormal vision J:231728
decreased a-wave amplitude J:231728
decreased b-wave amplitude J:231728
retina photoreceptor degeneration J:231728
Icmttm1Sgy/Icmttm1Sgy
Not Specified 		decreased body size J:67598
embryonic lethality during organogenesis, complete penetrance J:67598
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory