Clec7a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Clec7a
C-type lectin domain family 7, member a
MGI:1861431

16 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Clec7a^tm1.1Bpip/Clec7a^tm1.1Bpip Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129P2/OlaHsd * C57BL/6J	abnormal macrophage physiology	J:203908
	decreased tumor necrosis factor secretion	J:203908
	impaired macrophage phagocytosis	J:203908
	increased susceptibility to fungal infection	J:203908
Clec7a^tm1Gdb/Clec7a^tm1Gdb B6.129S6-Clec7a^tm1Gdb	abnormal circulating interleukin level	J:179011
	decreased circulating interleukin-17 level	J:179011
	increased susceptibility to fungal infection	J:179011
	lung inflammation	J:179011
Clec7a^tm1Gdb/Clec7a^tm1Gdb involves: 129S6/SvEvTac * C57BL/6	abnormal cytokine secretion	J:116669
	abnormal digestive system physiology	J:116669
	abnormal inflammatory response	J:116669
	abnormal macrophage physiology	J:116669
	abnormal neutrophil physiology	J:116669
	enlarged stomach	J:116669
	increased susceptibility to fungal infection	J:116669
	increased susceptibility to induced morbidity/mortality	J:116669
Clec7a^tm1Yiw/Clec7a^tm1Yiw C.129P2-Clec7a^tm1Yiw	abnormal cytokine secretion	J:116670
	abnormal dendritic cell physiology	J:116670
	abnormal macrophage physiology	J:116670
	increased susceptibility to fungal infection	J:116670
	lung cyst	J:116670
Clec7a^tm1Yiw/Clec7a^tm1Yiw involves: 129P2/OlaHsd * C57BL/6	abnormal dendritic cell physiology	J:122394
	normal immune system phenotype	J:122394

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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