Gtpbp2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gtpbp2
GTP binding protein 2
MGI:1860138

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gtpbp2^nmf205/Gtpbp2⁺ n-TRtct5^m1J/n-TRtct5^m1J C57BL/6J-Gtpbp2^nmf205/J	no abnormal phenotype detected	J:211326
Gtpbp2^nmf205/Gtpbp2^nmf205 n-TRtct5^m1J/n-TRtct5⁺ involves: 129S1/SvImJ * C57BL/6J	no abnormal phenotype detected	J:211326
Gtpbp2^nmf205/Gtpbp2^nmf205 n-TRtct5^m1J/n-TRtct5⁺ involves: A/J * C57BL/6J	no abnormal phenotype detected	J:211326
Gtpbp2^nmf205/Gtpbp2^nmf205 n-TRtct5^m1J/n-TRtct5⁺ involves: AKR/J * C57BL/6J	no abnormal phenotype detected	J:211326
Gtpbp2^nmf205/Gtpbp2^nmf205 n-TRtct5^m1J/n-TRtct5⁺ involves: C57BL/6J * C57BL/6NJ	no abnormal phenotype detected	J:211326
Gtpbp2^nmf205/Gtpbp2^nmf205 n-TRtct5^m1J/n-TRtct5⁺ involves: C57BL/6J * CBA/J	no abnormal phenotype detected	J:211326
Gtpbp2^nmf205/Gtpbp2^nmf205 n-TRtct5^m1J/n-TRtct5⁺ involves: C57BL/6J * DBA/2J	no abnormal phenotype detected	J:211326
Gtpbp2^nmf205/Gtpbp2^nmf205 n-TRtct5^m1J/n-TRtct5⁺ involves: C57BL/6J * MA/MyJ	no abnormal phenotype detected	J:211326
Gtpbp2^nmf205/Gtpbp2^nmf205 n-TRtct5^m1J/n-TRtct5⁺ involves: C57BL/6J * NOD/ShiLtJ	no abnormal phenotype detected	J:211326
Gtpbp2^nmf205/Gtpbp2^nmf205 n-TRtct5^m1J/n-TRtct5^m1J C57BL/6J-Gtpbp2^nmf205/J	abnormal cerebellar layer morphology	J:211326
	abnormal cerebellum morphology	J:211326
	abnormal dentate gyrus morphology	J:211326
	abnormal hippocampus CA2 region morphology	J:211326
	abnormal motor capabilities/coordination/movement	J:82238
	abnormal retina horizontal cell morphology	J:211326
	abnormal retina morphology	J:211326
	abnormal ribosomal stalling	J:211326
	amacrine cell degeneration	J:211326
	ataxia	J:211326
	decreased cerebellar granule cell number	J:211326
	increased neuron apoptosis	J:211326
	premature death	J:211326
	retina degeneration	J:211326
	retina ganglion cell degeneration	J:211326
	retina photoreceptor degeneration	J:211326
Gtpbp2^nmf205/Gtpbp2^nmf205 n-TRtct5^m1J/n-TRtct5^m1J Tg(n-TRtct1)516Slac/0 C57BL/6J-Gtpbp2^nmf205 Tg(n-TRtct1)516Slac	normal nervous system phenotype	J:297745
Gtpbp2^nmf205/Gtpbp2^nmf205 n-TRtct5^m1J/n-TRtct5^m1J Tg(n-TRtct2)557Slac/0 C57BL/6J-Gtpbp2^nmf205 Tg(n-TRtct2)557Slac	normal nervous system phenotype	J:297745
Gtpbp2^nmf205/Gtpbp2^nmf205 Tg(n-TRtct5)574Slac/0 involves: C57BL/6J	abnormal cerebellum morphology	J:211326
Gtpbp2^nmf205/Gtpbp2^nmf205 Tg(n-TRtct5)609Slac/0 C57BL/6J-Gtpbp2^nmf205 Tg(n-TRtct5)609Slac	abnormal cerebellum morphology	J:211326
Gtpbp2^nmf205/Gtpbp2^tm1Ynim n-TRtct5^m1J/n-TRtct5^m1J (C57BL/6J-Gtpbp2^nmf205/J x B6.Cg-Gtpbp2^tm1Ynim)F1	abnormal cerebellum morphology	J:211326
	neurodegeneration	J:211326
Gtpbp2^tm1Ynim/Gtpbp2^tm1Ynim n-TRtct5^m1J/n-TRtct5^m1J B6.Cg-Gtpbp2^tm1Ynim	abnormal cerebellar layer morphology	J:211326
	abnormal cerebellum morphology	J:211326
	increased neuron apoptosis	J:211326
	neurodegeneration	J:211326

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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