Ppm1d Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppm1d
protein phosphatase 1D magnesium-dependent, delta isoform
MGI:1858214

22 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppm1d^tm1Lad/Ppm1d^tm1Lad involves: 129S7/SvEvBrd	decreased pancreatic beta cell proliferation	J:151980
Ppm1d^tm1Lad/Ppm1d^tm1Lad involves: 129S7/SvEvBrd	impaired glucose tolerance	J:151980
Ppm1d^tm1Lad/Ppm1d^tm1Lad involves: 129S7/SvEvBrd * C57BL/6	abnormal epididymis morphology	J:74284
	chronic inflammation	J:74284
	decreased B cell proliferation	J:74284
	decreased body size	J:74284
	decreased CD8-positive, alpha-beta T cell number	J:74284
	decreased T cell proliferation	J:74284
	enlarged spleen	J:74284
	increased CD4-positive, alpha-beta T cell number	J:74284
	increased susceptibility to Orthomyxoviridae infection	J:74284
	lymphoid hyperplasia	J:74284
	male infertility	J:74284
	myeloid hyperplasia	J:74284
	oligozoospermia	J:74284
	premature death	J:74284
	prenatal lethality, incomplete penetrance	J:74284
	seminiferous tubule degeneration	J:74284
	skin lesions	J:74284
	small testis	J:74284
	small thymus	J:74284
	spleen hyperplasia	J:74284

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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