Plrg1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plrg1
pleiotropic regulator 1
MGI:1858197

14 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plrg1^tm1Jcbr/Plrg1^tm1Jcbr Not Specified	embryonic lethality before implantation, complete penetrance	J:149153
Plrg1^tm2Jcbr/Plrg1^tm2Jcbr Not Specified	abnormal cell cycle	J:149153
Plrg1^tm2Jcbr/Plrg1^tm2Jcbr Not Specified	decreased cell proliferation	J:149153
Plrg1^tm2Jcbr/Plrg1^tm2Jcbr Tg(Ckmm-cre)5Khn/0 involves: FVB	abnormal heart ventricle morphology	J:149153
	decreased heart ventricle muscle contractility	J:149153
	dilated cardiomyopathy	J:149153
	dilated heart	J:149153
	dilated heart left ventricle	J:149153
	dilated heart right ventricle	J:149153
	increased cardiomyocyte apoptosis	J:149153
	premature death	J:149153
	thin ventricular wall	J:149153
Plrg1^tm2Jcbr/Plrg1^tm2Jcbr Tg(Syn1-cre)671Jxm/0 involves: C57BL/6 * CBA	increased neuron apoptosis	J:149153
	postnatal lethality, complete penetrance	J:149153

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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