83 phenotypes from 9 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Socs1tm1.1(KOMP)Vlcg/Socs1tm1.1(KOMP)Vlcg C57BL/6N-Socs1tm1.1(KOMP)Vlcg/Tcp	preweaning lethality, complete penetrance	J:211773
Socs1tm1.1Ayr/Socs1tm1.1Ayr involves: C57BL/6	abnormal T cell physiology	J:226678
	decreased effector memory T-helper cell number	J:226678
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:226678
Socs1tm1Ayos/Socs1tm1Ayos involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:132905
Socs1tm1Ayos/Socs1tm1Ayos Foxp3tm4(YFP/icre)Ayr/Foxp3+ involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	blepharitis	J:167922
	conjunctivitis	J:167922
	dermatitis	J:167922
	increased regulatory T cell number	J:167922
Socs1tm1Ayos/Socs1tm1Ayos Tg(Lck-cre)1Jtak/0 involves: 129S4/SvJae * C57BL/6	abnormal CD4-positive T cell differentiation	J:132905
	abnormal CD4-positive, alpha-beta T cell physiology	J:132905
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:132905
Socs1tm1Ayos/Socs1tm1Ayos Tg(Tek-cre)1Ywa/0 involves: 129S4/SvJae * C57BL/6 * SJL	decreased CD4-positive, alpha-beta T cell number	J:132905
	increased CD8-positive, alpha-beta T cell number	J:132905
	premature death	J:132905
Socs1tm1Jni/Socs1+ Not Specified	abnormal cytokine level	J:91651
	abnormal interleukin level	J:91651
	abnormal liver morphology	J:91651
	increased hepatoma incidence	J:91651
	increased susceptibility to xenobiotic induced morbidity/mortality	J:91651
Socs1tm1Jni/Socs1tm1Jni Not Specified	abnormal cytokine secretion	J:57475
	abnormal T cell differentiation	J:57475
	decreased B cell number	J:57475
	decreased thymocyte number	J:57475
	postnatal lethality, complete penetrance	J:57475
Socs1tm1Kish/Socs1tm1Kish B6.129P2-Socs1tm1Kish	abnormal lymphocyte physiology	J:69472
	decreased body size	J:69472
	enlarged liver	J:69472
	increased activated T cell number	J:69472
	increased NK T cell number	J:69472
	increased susceptibility to injury	J:69472
	liver inflammation	J:69472
	postnatal lethality, complete penetrance	J:69472
	thymus atrophy	J:69472
Socs1tm1Kish/Socs1tm1Kish involves: 129P2/OlaHsd * C57BL/6J	abnormal spleen morphology	J:51685
	abnormal spleen white pulp morphology	J:51685
	absent thymus corticomedullary boundary	J:51685
	decreased lymphocyte cell number	J:51685
	enlarged liver	J:51685
	postnatal growth retardation	J:51685
	postnatal lethality, complete penetrance	J:51685
Socs1tm1Wehi/Socs1tm1Wehi involves: 129S1/Sv * C57BL/6	abnormal follicular B cell morphology	J:51281
	abnormal inflammatory response	J:57474
	abnormal lymph node B cell domain morphology	J:51281
	abnormal macrophage physiology	J:57474
	abnormal mature B cell morphology	J:51281
	abnormal Peyer's patch morphology	J:51281
	abnormal pulmonary alveolus wall morphology	J:51281
	abnormal spleen white pulp morphology	J:57474
	decreased B cell number	J:51281
	decreased body weight	J:51281
	decreased bone marrow cell number	J:57474
	decreased eosinophil cell number	J:51281
	decreased hematocrit	J:51281
	decreased leukocyte cell number	J:57474
	decreased lymphocyte cell number	J:51281
	decreased pre-B cell number	J:51281
	decreased susceptibility to Togaviridae infection induced morbidity/mortality	J:57474
	heart inflammation	J:51281
	normal hematopoietic system phenotype	J:57474
	hepatic necrosis	J:57474
	hepatic steatosis	J:51281, J:57474
	increased inflammatory response	J:72528
	increased spleen red pulp amount	J:51281
	liver degeneration	J:51281
	liver inflammation	J:51281
	pancreas inflammation	J:51281
	postnatal growth retardation	J:51281
	postnatal lethality, complete penetrance	J:51281, J:57474, J:72528
	small thymus	J:51281
	thick epidermis	J:57474
	thrombocytopenia	J:51281
	thymus cortex atrophy	J:51281, J:57474
Socs1tm1Wehi/Socs1tm3Wehi Tg(Lck-cre)I57Jxm/0 involves: 129P2/OlaHsd * C57BL/6 * ICR	abnormal CD4-positive, alpha beta T cell morphology	J:83009
	abnormal CD8-positive, alpha beta T cell morphology	J:83009
	abnormal T cell activation	J:83009
	abnormal T cell differentiation	J:83009
	abnormal T cell subpopulation ratio	J:83009
	decreased B cell number	J:83009
	enlarged lymph nodes	J:83009
	enlarged thymus medulla	J:83009
	increased CD4-positive, alpha-beta T cell number	J:83009
	increased CD8-positive, alpha-beta T cell number	J:83009
	lymph node hyperplasia	J:83009
	thymus hyperplasia	J:83009
Socs1tm2Wehi/Socs1tm2Wehi C57BL/6-Socs1tm2Wehi	absent spleen germinal center	J:72528
	decreased body weight	J:72528
	extramedullary hematopoiesis	J:72528
	glomerulonephritis	J:72528
	increased incidence of corneal inflammation	J:72528
	increased inflammatory response	J:72528
	intestinal inflammation	J:72528
	liver inflammation	J:72528
	myocarditis	J:72528
	myositis	J:72528
	pancreas inflammation	J:72528
	premature death	J:72528
	salivary gland inflammation	J:72528
	skin inflammation	J:72528
	thymus atrophy	J:72528
Socs1tm3.1Wehi/Socs1tm3.1Wehi C57BL/6-Socs1tm3.1Wehi	abnormal inflammatory response	J:83009
	increased circulating interferon-gamma level	J:83009
	preweaning lethality, incomplete penetrance	J:83009
Socs1tm3Wehi/Socs1tm3Wehi C57BL/6-Socs1tm3Wehi	no abnormal phenotype detected	J:83009