E2f6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

E2f6
E2F transcription factor 6
MGI:1354159

22 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
\E2f6^{em1(IMPC)Ccpcz}/\E2f6^{em1(IMPC)Ccpcz} C57BL/6NCrl-E2f6^{em1(IMPC)Ccpcz}/Ccpcz	abnormal heart morphology	J:211773
	abnormal seminal vesicle morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal thymus morphology	J:211773
	abnormal tooth color	J:211773
	abnormal tooth morphology	J:211773
	abnormal urinary bladder morphology	J:211773
	abnormal vocalization	J:211773
	enlarged heart	J:211773
	enlarged urinary bladder	J:211773
	small seminal vesicle	J:211773
	small spleen	J:211773
	small thymus	J:211773
\E2f6^tm1Hgmr/\E2f6^tm1Hgmr involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:99185
\E2f6^tm1Lees/\E2f6⁺ involves: 129S4/SvJae * C57BL/6	lumbar vertebral transformation	J:134271
\E2f6^tm1Lees/\E2f6⁺ involves: 129S4/SvJae * C57BL/6	thoracic vertebral transformation	J:134271
\E2f6^tm1Lees/\E2f6^tm1Lees involves: 129S4/SvJae * C57BL/6	normal cellular phenotype	J:134271
	cervical vertebral transformation	J:134271
	normal hematopoietic system phenotype	J:134271
	lumbar vertebral transformation	J:134271
	thoracic vertebral transformation	J:134271
\E2f6^tm1Sgau/\E2f6⁺ involves: 129S4/SvJae * C57BL/6	lumbar vertebral transformation	J:106219
\E2f6^tm1Sgau/\E2f6^tm1Sgau involves: 129S4/SvJae * C57BL/6	normal cellular phenotype	J:106219
	increased Leydig cell number	J:106219
	lumbar vertebral transformation	J:106219
	oligozoospermia	J:106219
	thoracic vertebral transformation	J:106219

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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