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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Glrx3
glutaredoxin 3
MGI:1353653
26 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Glrx3Gt(RRF094)Byg/Glrx3+
involves: 129P2/OlaHsd * C57BL/6
abnormal cardiac muscle relaxation J:143577
abnormal myocardial fiber physiology J:143577
decreased cardiac muscle contractility J:143577
increased response of heart to induced stress J:143577
Glrx3Gt(RRF094)Byg/Glrx3Gt(RRF094)Byg
involves: 129P2/OlaHsd * C57BL/6
abnormal cell cycle J:190794
abnormal cell death J:190794
binucleate J:190794
decreased embryo size J:143577, J:190794
decreased fibroblast proliferation J:190794
embryonic lethality during organogenesis, complete penetrance J:190794
embryonic lethality during organogenesis, incomplete penetrance J:143577
intracranial hemorrhage J:143577
lethality throughout fetal growth and development, complete penetrance J:143577
open neural tube J:190794
pericardial effusion J:190794
Glrx3tm1.1(KOMP)Vlcg/Glrx3+
C57BL/6N-Glrx3tm1.1(KOMP)Vlcg/J
increased circulating alkaline phosphatase level J:211773
Glrx3tm1.1(KOMP)Vlcg/Glrx3tm1.1(KOMP)Vlcg
B6N(Cg)-Glrx3tm1.1(KOMP)Vlcg/J
abnormal egg cylinder morphology J:279207
absent head fold J:279207
absent primitive node J:279207
decreased embryo size J:279207
embryonic growth arrest J:279207
embryonic lethality prior to organogenesis J:279207
embryonic lethality, complete penetrance J:279207
failure of primitive streak formation J:279207
failure to gastrulate J:279207
Glrx3tm1.1(KOMP)Vlcg/Glrx3tm1.1(KOMP)Vlcg
C57BL/6N-Glrx3tm1.1(KOMP)Vlcg/J
embryonic lethality prior to organogenesis J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory