Plcl2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plcl2
phospholipase C-like 2
MGI:1352756

15 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plcl2^{em1(IMPC)Hmgu}/Plcl2^{em1(IMPC)Hmgu} C57BL/6NCrl-Plcl2^{em1(IMPC)Hmgu}/Ieg	increased eosinophil cell number	J:211773
	increased leukocyte cell number	J:211773
	increased lymphocyte cell number	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular volume	J:211773
	increased monocyte cell number	J:211773
	increased neutrophil cell number	J:211773
Plcl2^tm1Tta/Plcl2^tm1Tta involves: 129P2/OlaHsd	abnormal adaptive immunity	J:85960
	abnormal B cell calcium ion homeostasis	J:85960
	abnormal calcium ion homeostasis	J:85960
	decreased B-1a cell number	J:85960
	decreased mature B cell number	J:85960
	increased anti-nuclear antigen antibody level	J:85960
	increased B cell proliferation	J:85960
	increased IgM level	J:85960

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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