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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
MGI:1351481
8 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pdk1tm1a(EUCOMM)Hmgu/Pdk1tm1a(EUCOMM)Hmgu
Pdk2tm1Rhar/Pdk2tm1Rhar
Pdk3em1Eze/Pdk3em1Eze
Pdk4tm1Rhar/Pdk4tm1Rhar
involves: 129 * C57BL/6J * C57BL/6N 		abnormal circulating protein level J:303714
decreased circulating glucose level J:303714
decreased circulating lactate level J:303714
increased circulating ketone body level J:303714
postnatal lethality, complete penetrance J:303714
normal skeleton phenotype J:303714
Pdk1tm1a(EUCOMM)Hmgu/Pdk1tm1a(EUCOMM)Hmgu
Pdk2tm1Rhar/Pdk2tm1Rhar
Pdk4tm1Rhar/Pdk4tm1Rhar
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		mortality/aging J:303714
reproductive system phenotype J:303714
skeleton phenotype J:303714
Pdk1tm1a(EUCOMM)Hmgu/Pdk1tm1a(EUCOMM)Hmgu
Pdk4tm1Rhar/Pdk4tm1Rhar
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		mortality/aging J:303714
reproductive system phenotype J:303714
skeleton phenotype J:303714
Pdk1tm1c(EUCOMM)Hmgu/Pdk1tm1c(EUCOMM)Hmgu
Pdk2tm1Rhar/Pdk2tm1Rhar
Pdk3em1Eze/Pdk3em1Eze
Pdk4tm1Rhar/Pdk4tm1Rhar
Tg(Prrx1-cre)1Cjt/0
involves: 129 * C57BL/6J * C57BL/6N * SJL/J 		normal mortality/aging J:303714
normal reproductive system phenotype J:303714
normal skeleton phenotype J:303714
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory