Nherf1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nherf1
NHERF family PDZ scaffold protein 1
MGI:1349482

18 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nherf1^em1(IMPC)H/Nherf1^em1(IMPC)H C57BL/6NTac-Nherf1^em1(IMPC)H/H	decreased circulating iron level	J:211773
	increased basophil cell number	J:211773
	increased leukocyte cell number	J:211773
Nherf1^tm1Geo/Nherf1^tm1Geo involves: C57BL/6J	abnormal intestinal epithelium morphology	J:95282
	abnormal intestinal goblet cell morphology	J:95282
	abnormal intestine morphology	J:95282
	decreased circulating phosphate level	J:95282
	premature death	J:95282
Nherf1^tm1Ssl/Nherf1^tm1Ssl FVB.129-Nherf1^tm1Ssl	abnormal physiological response to xenobiotic	J:128912
Nherf1^tm1Ssl/Nherf1^tm1Ssl FVB.129-Nherf1^tm1Ssl	normal reproductive system phenotype	J:128912
Nherf1^tm1Ssl/Nherf1^tm1Ssl involves: 129X1/SvJ	decreased litter size	J:78606
Nherf1^tm1Ssl/Nherf1^tm1Ssl involves: 129X1/SvJ	reduced fertility	J:78606
Nherf1^tm1Ssl/Nherf1^tm1Ssl involves: 129X1/SvJ * C57BL/6	abnormal locomotor behavior	J:78606
	decreased bone mineral content	J:78606
	decreased bone mineral density	J:78606
	decreased litter size	J:78606
	hydrocephaly	J:78606
	increased urine phosphate level	J:78606
	premature death	J:78606
	prenatal lethality, incomplete penetrance	J:78606

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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