43 phenotypes from 2 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cln8em1(IMPC)Mbp/Cln8em1(IMPC)Mbp C57BL/6N-Cln8em1(IMPC)Mbp/MbpMmucd	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	enlarged heart	J:211773
	enlarged kidney	J:211773
	enlarged spleen	J:211773
	increased circulating phosphate level	J:211773
	increased circulating serum albumin level	J:211773
	increased heart weight	J:211773
	small liver	J:211773
Cln8mnd/Cln8+ involves: B6.KB2 * C57BL/6Fla	abnormal motor neuron morphology	J:8492, J:218228
Cln8mnd/Cln8mnd AK.B6(Cg)-Cln8mnd	abnormal motor neuron morphology	J:56219
	premature death	J:56219
Cln8mnd/Cln8mnd B6.KB2/Rn-Cln8mnd	abnormal cranial nerve morphology	J:8492
	abnormal hypoglossal nerve morphology	J:8492
	abnormal locomotor behavior	J:8492
	abnormal motor capabilities/coordination/movement	J:8492
	abnormal motor neuron morphology	J:8492, J:56219
	abnormal nervous system morphology	J:12816
	abnormal retina photoreceptor layer morphology	J:12816
	abnormal spinal cord ventral horn morphology	J:8492
	abnormal vagus nerve morphology	J:8492
	ataxia	J:8492
	blindness	J:12816
	decreased litter size	J:8492
	hindlimb paralysis	J:8492
	limb grasping	J:8492
	motor neuron degeneration	J:8492
	paralysis	J:12816
	paresis	J:12816
	premature death	J:8492, J:56219
Cln8mnd/Cln8mnd involves: AKR/J * B6.KB2	abnormal motor neuron morphology	J:56219
	abnormal nervous system morphology	J:1224
	abnormal retina photoreceptor layer morphology	J:19328
	abnormal retina pigment epithelium morphology	J:19328
	abnormal retina rod cell inner segment morphology	J:19328
	abnormal retina rod cell outer segment morphology	J:19328
	increased susceptibility to age-related retinal degeneration	J:19328
	premature death	J:1224, J:56219
	short photoreceptor inner segment	J:19328
	short photoreceptor outer segment	J:19328
	thin retina outer nuclear layer	J:19328
Cln8mnd/Cln8mnd involves: B6.KB2	abnormal myelination	J:47292
	axon degeneration	J:47292
	gliosis	J:47292
	seizures	J:47292
Cln8mnd/Cln8mnd involves: B6.KB2 * C3H/HeJ	abnormal motor neuron morphology	J:56219
	abnormal nervous system morphology	J:1224
	premature death	J:1224, J:56219