Adamts2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adamts2
ADAM metallopeptidase with thrombospondin type 1 motif 2
MGI:1347356

39 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adamts2^{em1(IMPC)Ccpcz}/Adamts2⁺ C57BL/6NCrl-Adamts2^{em1(IMPC)Ccpcz}/Ccpcz	abnormal heart morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal thymus morphology	J:211773
	enlarged heart	J:211773
	enlarged thymus	J:211773
	increased circulating creatinine level	J:211773
	small spleen	J:211773
	small testis	J:211773
Adamts2^{em1(IMPC)Ccpcz}/Adamts2^{em1(IMPC)Ccpcz} C57BL/6NCrl-Adamts2^{em1(IMPC)Ccpcz}/Ccpcz	abnormal epididymis morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal tail morphology	J:211773
	abnormal thymus morphology	J:211773
	decreased lung compliance	J:211773
	enlarged epididymis	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
	female infertility	J:211773
	increased freezing behavior	J:211773
	increased lung elastance	J:211773
	increased lung tissue damping	J:211773
Adamts2^tm1Dgen/Adamts2^tm1Dgen involves: 129P2/OlaHsd * C57BL/6J	no abnormal phenotype detected	J:82809
Adamts2^tm1Prc/Adamts2^tm1Prc involves: 129	abnormal cutaneous collagen fibril morphology	J:69141
	abnormal hair follicle morphology	J:69141
	abnormal molar morphology	J:107394
	abnormal spermatogenesis	J:69141
	abnormal xiphoid process morphology	J:69141
	emphysema	J:107394
	male infertility	J:69141
	oligozoospermia	J:69141
	short snout	J:69141
	thin skin	J:69141
	triangular face	J:69141
Adamts2^tm1Prc/Adamts2^tm1Prc involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cutaneous collagen fibril morphology	J:271185
	abnormal homeostasis	J:271185
	abnormal tendon collagen fibril morphology	J:271185
	decreased skin tensile strength	J:271185
	normal homeostasis/metabolism phenotype	J:271185
	increased interferon-gamma secretion	J:271185
	normal integument phenotype	J:271185
	male infertility	J:271185
	ruffled hair	J:271185
	normal vision/eye phenotype	J:271185

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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