Hsf4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hsf4
heat shock transcription factor 4
MGI:1347058

15 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hsf4^ldis1/Hsf4^ldis1 either: RIIIS/J or (involves: DBA/2J * RIIIS/J)	abnormal lens epithelium morphology	J:93209
	abnormal lens fiber morphology	J:93209
	cataract	J:93209
	lens dislocation	J:93209
	microphthalmia	J:93209
	small lens	J:93209
Hsf4^ldis1/Hsf4^ldis1 involves: C57BL/6 * CAST/EiJ * RIIIS/J	cataract	J:179658
Hsf4^tm1Anak/Hsf4^tm1Anak either: (involves: C57BL/6 * CBA) or (involves: C57BL/6 * CBA * ICR)	abnormal lens capsule morphology	J:93301
	abnormal lens epithelium morphology	J:93301
	abnormal lens morphology	J:93301
	cataract	J:93301
	hydropic eye lens fibers	J:93301
	ruptured lens capsule	J:93301
Hsf4^{tm1b(KOMP)Wtsi}/Hsf4^{tm1b(KOMP)Wtsi} C57BL/6N-Hsf4^{tm1b(KOMP)Wtsi}/J	abnormal cornea morphology	J:211773
	abnormal iris pigmentation	J:211773
	abnormal lens morphology	J:211773
	cataract	J:211773
	increased circulating alanine transaminase level	J:211773
	irregularly shaped pupil	J:211773
Hsf4^tm1Miv/Hsf4^tm1Miv involves: 129S2/SvPas * C57BL/6	abnormal lens fiber morphology	J:95535
	abnormal lens morphology	J:95535
	cataract	J:95535
	microphthalmia	J:95535
Hsf4^tm1Xyk/Hsf4^tm1Xyk involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal lens fiber morphology	J:149354
	abnormal lens morphology	J:149354
Tg(Hsf4/EGFP)N7Spbh/0 C57BL/6-Tg(Hsf4/EGFP)N7Spbh	abnormal lens epithelium morphology	J:230205
	abnormal lens fiber morphology	J:230205
	abnormal lens morphology	J:230205
	lamellar cataract	J:230205

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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