Angptl2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Angptl2
angiopoietin-like 2
MGI:1347002

15 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Angptl2^tm1Yo/Angptl2^tm1Yo B6.Cg-Angptl2^tm1Yo	decreased body weight	J:152387
	decreased respiratory quotient	J:152387
	decreased subcutaneous adipose tissue amount	J:152387
	decreased total body fat amount	J:152387
	impaired macrophage chemotaxis	J:152387
	improved glucose tolerance	J:152387
	increased insulin sensitivity	J:152387
Tg(Fabp4-Angptl2)5Yo/0 involves: C57BL/6	abnormal macrophage chemotaxis	J:152387
	chronic inflammation	J:152387
	impaired glucose tolerance	J:152387
	insulin resistance	J:152387
	white adipose tissue inflammation	J:152387
Tg(Krt14-Angptl2)1Yo/0 C.Cg-Tg(Krt14-Angptl2)1Yo	abnormal tail tip morphology	J:152387
	normal muscle phenotype	J:181261
	skin inflammation	J:152387, J:181261

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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