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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Map2k7
mitogen-activated protein kinase kinase 7
MGI:1346871
12 phenotypes from 8 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Map2k7tm1.1Twad/Map2k7tm1.1Twad
B6.Cg-Map2k7tm1.1Twad 		no abnormal phenotype detected J:170904
Map2k7tm1.1Twad/Map2k7tm1.1Twad
Tg(KRT5-cre)1Tak/0
involves: 129P2/OlaHsd * C3H * C57BL/6 		eyelids open at birth J:170904
Map2k7tm1.1Twad/Map2k7tm1.2Twad
Tg(MMTV-cre)4Mam/0
involves: 129P2/OlaHsd * C57BL/6 * FVB 		normal reproductive system phenotype J:170904
Map2k7tm1a(EUCOMM)Wtsi/Map2k7tm1a(EUCOMM)Wtsi
C57BL/6N-Map2k7tm1a(EUCOMM)Wtsi/Wtsi 		preweaning lethality, complete penetrance J:211773
Map2k7tm1Flv/Map2k7tm1Flv
involves: 129S1/Sv 		embryonic lethality, complete penetrance J:61895
Map2k7tm1Pngr/Map2k7+
involves: 129P2/OlaHsd * C57BL/6J 		abnormal spatial working memory J:188339
Map2k7tm1Rjd/Map2k7tm1Rjd
Tg(CAG-cre/Esr1*)5Amc/0
involves: C57BL/6 * CBA 		normal nervous system phenotype J:178060
Map2k7tm2.1Rjd/Map2k7tm2.1Rjd
B6.129S6-Map2k7tm2.1Rjd 		embryonic lethality, complete penetrance J:101977
Tg(Myh6-Map2k7)1Jmol/0
involves: FVB/N 		abnormal cardiac muscle contractility J:102152
cardiac hypertrophy J:102152
decreased cardiomyocyte apoptosis J:102152
decreased myocardial infarct size J:102152
increased heart weight J:102152
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory