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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sgcg
sarcoglycan, gamma (dystrophin-associated glycoprotein)
MGI:1346524
40 phenotypes from 5 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sgcgem1Mcn/Sgcgem1Mcn
D2.B6-Sgcgem1Mcn 		abnormal muscle physiology J:285272
abnormal respiratory function J:285272
abnormal skeletal muscle fiber morphology J:285272
calcified muscle J:285272
cardiac fibrosis J:285272
decreased grip strength J:285272
decreased skeletal muscle fiber diameter J:285272
decreased skeletal muscle mass J:285272
dystrophic muscle J:285272
impaired skeletal muscle contractility J:285272
increased circulating creatine kinase level J:285272
increased variability of skeletal muscle fiber size J:285272
myopathy J:285272
myositis J:285272
skeletal muscle fibrosis J:285272
skeletal muscle necrosis J:285272
Sgcgtm1Mcn/Sgcgtm1Mcn
involves: 129X1/SvJ * C57BL/6 		abnormal diaphragm morphology J:49871
abnormal gait J:49871
abnormal heart ventricle morphology J:49871
normal behavior/neurological phenotype J:57664
coronary artery spasm J:88456
decreased body weight J:49871, J:57664
decreased heart weight J:49871
decreased locomotor activity J:49871
dystrophic muscle J:49871
increased circulating creatine kinase level J:49871, J:57664
normal muscle phenotype J:57664
premature death J:49871
thick diaphragm muscle J:49871
thick ventricular wall J:49871
Sgcgtm1Oza/Sgcgtm1Oza
involves: 129S4/SvJae * C57BL/6 		abnormal diaphragm morphology J:102780
abnormal muscle regeneration J:102780
abnormal tibialis anterior morphology J:102780
cardiac fibrosis J:102780
dystrophic muscle J:102780
increased circulating creatine kinase level J:102780
increased skeletal muscle fiber size J:102780
increased skeletal muscle mass J:102780
muscle degeneration J:102780
myocardium necrosis J:102780
premature death J:102780
progressive muscle weakness J:102780
skeletal muscle hypertrophy J:102780
skeletal muscle interstitial fibrosis J:102780
skeletal muscle necrosis J:102780
Tg(Ckm-Sgcg)4Mcn/0
involves: C57BL/6 * DBA/2 		abnormal gait J:128649
abnormal skeletal muscle morphology J:128649
centrally nucleated skeletal muscle fibers J:128649
decreased body size J:128649
decreased locomotor activity J:128649
decreased skeletal muscle mass J:128649
dystrophic muscle J:128649
increased variability of skeletal muscle fiber size J:128649
premature death J:128649
Tg(Ckm-Sgcg)5Mcm/0
involves: C57BL/6 * DBA/2 		abnormal gait J:128649
decreased body size J:128649
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/16/2026
MGI 6.24 		The Jackson Laboratory