Hs2st1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hs2st1
heparan sulfate 2-O-sulfotransferase 1
MGI:1346049

19 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hs2st1^{Gt(pGT1.8TM)ST125Nimr}/Hs2st1^{Gt(pGT1.8TM)ST125Nimr} involves: 129P2/OlaHsd * C57BL/6	abnormal bone mineralization	J:48481
	abnormal eye development	J:48481
	abnormal kidney development	J:48481
	abnormal retina pigment epithelium morphology	J:48481
	abnormal sternum ossification	J:48481
	abnormal ureteric bud morphology	J:48481
	absent kidney	J:48481
	cataract	J:48481
	cervical vertebral fusion	J:48481
	cleft secondary palate	J:48481
	impaired branching involved in ureteric bud morphogenesis	J:48481
	iris coloboma	J:48481
	perinatal lethality, complete penetrance	J:48481
	polydactyly	J:48481
Hs2st1^{Gt(pGT1.8TM)ST125Nimr}/Hs2st1^{Gt(pGT1.8TM)ST125Nimr} involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal retina ganglion cell morphology	J:110040
Hs2st1^tm1.1Je/Hs2st1^tm1.1Je Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ B6.Cg-Hs2st1^tm1.1Je Speer6-ps1^{Tg(Alb-cre)21Mgn}	abnormal hepatocyte physiology	J:158299
	abnormal lipid homeostasis	J:158299
	increased circulating triglyceride level	J:158299
Hs2st1^tm1.2Je/Hs2st1^tm1.2Je involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J	absent kidney	J:158299
	neonatal lethality, complete penetrance	J:158299

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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