Sufu Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sufu
SUFU negative regulator of hedgehog signaling
MGI:1345643

5 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gli3^tm1Urt/Gli3^tm1Urt Sufu^tm1.1Blnw/Sufu^tm1.1Blnw involves: 129 * C57BL/6 * CD-1 * FVB/N	normal nervous system phenotype	J:161408
Sufu^Gt(XB699)Byg/Sufu⁺ Trp53^tm1Tyj/Trp53^tm1Tyj involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	increased lymphoma incidence	J:125534
	increased medulloblastoma incidence	J:125534
	increased rhabdomyosarcoma incidence	J:125534
	premature death	J:125534

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24