Ddr2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ddr2
discoidin domain receptor family, member 2
MGI:1345277

3 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ddr1^tm1Wfv/Ddr1^tm1Wfv Ddr2^tm1Kln/Ddr2^tm1Kln involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cranium morphology	J:123719
Ddr2^{tm1a(EUCOMM)Wtsi}/Ddr2^{tm1a(EUCOMM)Wtsi} Tg(MMTV-PyVT)634Mul/0 involves: C57BL/6N * FVB/N	decreased metastatic potential	J:236031
	increased mammary gland tumor incidence	J:236031
Ddr2^{tm1b(EUCOMM)Wtsi}/Ddr2^{tm1b(EUCOMM)Wtsi} Tg(MMTV-PyVT)634Mul/0 involves: C57BL/6N * FVB/N	decreased metastatic potential	J:236031
	increased mammary gland tumor incidence	J:236031
Ddr2^{tm1c(EUCOMM)Wtsi}/Ddr2^{tm1c(EUCOMM)Wtsi} Tg(KRT14-cre)1Amc/0 Tg(MMTV-PyVT)634Mul/0 involves: C57BL/6 * C57BL/6N * CBA * FVB/N	decreased metastatic potential	J:236031
	increased mammary gland tumor incidence	J:236031
Ddr2^{tm1c(EUCOMM)Wtsi}/Ddr2^{tm1c(EUCOMM)Wtsi} Tg(MMTV-cre)#Mam/0 Tg(MMTV-PyVT)634Mul/0 involves: C57BL/6N * FVB * FVB/N	increased mammary gland tumor incidence	J:236031

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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