Ly96 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ly96
lymphocyte antigen 96
MGI:1341909

10 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ly96^m1Btlr/Ly96^m1Btlr C57BL/6J-Ly96^m1Btlr	decreased interleukin-1 beta secretion	J:265259
	decreased macrophage apoptosis	J:265259
	decreased tumor necrosis factor secretion	J:265259
Ly96^tm1Kmiy/Ly96^tm1Kmiy involves: 129P2/OlaHsd * C57BL/6	abnormal immune cell physiology	J:92494
	abnormal macrophage physiology	J:92494
	decreased B cell proliferation	J:92494
	decreased interleukin-6 secretion	J:92494
	decreased susceptibility to endotoxin shock	J:92494
	decreased tumor necrosis factor secretion	J:92494
	impaired neutrophil recruitment	J:92479
	increased susceptibility to bacterial infection	J:92494

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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