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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tjp2
tight junction protein 2
MGI:1341872
13 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tjp2tm1Whun/Tjp2tm1Whun
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6)
abnormal plasma membrane morphology J:132649
absent mesoderm J:132649
decreased cell proliferation J:132649
decreased embryo size J:132649
disorganized embryonic tissue J:132649
embryonic growth arrest J:132649
embryonic lethality between implantation and somite formation, complete penetrance J:132649
failure to gastrulate J:132649
increased embryonic tissue cell apoptosis J:132649
Tjp2tm2Whun/Tjp2tm2Whun
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac * DBA/2
increased circulating alanine transaminase level J:306936
increased circulating aspartate transaminase level J:306936
increased circulating LDL cholesterol level J:306936
normal liver/biliary system phenotype J:306936

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory