Fanca Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fanca
Fanconi anemia, complementation group A
MGI:1341823

38 phenotypes from 5 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fanca^tm1.1Wong/Fanca^tm1.1Wong involves: 129S6/SvEvTac	normal vision/eye phenotype	J:85108
Fanca^tm1.1Wong/Fanca^tm1.1Wong involves: C57BL/6	abnormal cell physiology	J:85108
	abnormal cranium morphology	J:85108
	decreased body weight	J:85108
	decreased germ cell number	J:85108
	decreased testis weight	J:85108
	embryonic growth retardation	J:85108
	microphthalmia	J:85108
	reduced female fertility	J:85108
	seminiferous tubule degeneration	J:85108
Fanca^{tm1a(EUCOMM)Wtsi}/Fanca^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	increased physiological sensitivity to xenobiotic	J:188123
	increased sensitivity to induced cell death	J:188123
Fanca^tm1Faw/Fanca⁺ involves: 129P2/OlaHsd * FVB	induced chromosome breakage	J:63742
Fanca^tm1Faw/Fanca^tm1Faw involves: 129P2/OlaHsd * FVB	abnormal ovary morphology	J:63742
	abnormal spermatogenesis	J:63742
	absent mature ovarian follicles	J:63742
	decreased litter size	J:63742
	increased Leydig cell number	J:63742
	increased mean corpuscular volume	J:63742
	induced chromosome breakage	J:63742
	reduced female fertility	J:63742
	reduced male fertility	J:63742
	normal skeleton phenotype	J:63742
	small gonad	J:63742
	small seminiferous tubules	J:63742
	spontaneous chromosome breakage	J:63742
	thrombocytopenia	J:63742
Fanca^tm1Faw/Fanca^tm1Faw involves: 129P2/OlaHsd * FVB/N	abnormal chromosome morphology	J:144998
Fanca^tm1Wong/Fanca^tm1Wong either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * CD-1)	normal neoplasm	J:85108
	seminiferous tubule degeneration	J:85108
Fanca^tm1Wong/Fanca^tm1Wong either: 129S6/SvEvTac or C57BL/6	abnormal ovary morphology	J:85108
	decreased mature ovarian follicle number	J:85108
	ovary cyst	J:85108
	ovary hemorrhage	J:85108
	ovary hypoplasia	J:85108
	small ovary	J:85108
Fanca^tm1Wong/Fanca^tm1Wong involves: 129S6/SvEvTac	abnormal male meiosis	J:85108
	abnormal spermatogenesis	J:85108
	decreased germ cell number	J:85108
	early reproductive senescence	J:85108
	increased male germ cell apoptosis	J:85108
	reduced female fertility	J:85108
	seminiferous tubule degeneration	J:85108
	small testis	J:85108
Fanca^tm1Wong/Fanca^tm1Wong involves: C57BL/6	abnormal cranium morphology	J:85108
	decreased body weight	J:85108
	decreased germ cell number	J:85108
	microphthalmia	J:85108
	postnatal growth retardation	J:85108
	small testis	J:85108
Fanca^tm1Zqw/Fanca^tm1Zqw involves: 129P2/OlaHsd	chromosome breakage	J:102526

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