Adam22 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adam22
a disintegrin and metallopeptidase domain 22
MGI:1340046

12 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adam22^tm1.1Mejr/Adam22^tm1.1Mejr H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S4/SvJaeSor * C57BL/6J * CBA/J	abnormal myelination	J:158973
	abnormal neuron morphology	J:158973
Adam22^tm1.1Mejr/Adam22^tm1.1Mejr Tg(Dhh-cre)1Mejr/0 involves: 129S4/SvJaeSor * FVB/N	normal nervous system phenotype	J:158973
Adam22^tm1Sag/Adam22^tm1Sag either: B6.Cg-Adam22^tm1Sag or (involves: C57BL/6 * C57BL/6N * CBA)	abnormal myelination	J:99692
	abnormal Schwann cell morphology	J:99692
	ataxia	J:99692
	convulsive seizures	J:99692
	decreased body size	J:99692
	decreased body weight	J:99692
	postnatal lethality, complete penetrance	J:99692
Adam22^tm1Sag/Adam22^tm1Sag involves: C57BL/6 * CBA	abnormal glial cell morphology	J:166449
	abnormal neuron morphology	J:158973
	decreased body weight	J:166449
	demyelination	J:158973, J:166449
	neonatal lethality, incomplete penetrance	J:166449

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/07/2025 MGI 6.24