P2rx4 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

P2rx4
purinergic receptor P2X, ligand-gated ion channel 4
MGI:1338859

13 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
P2rx4^tm1Ando/P2rx4^tm1Ando involves: 129S4/SvJae * BALB/c * C57BL/6	abnormal neutrophil physiology	J:311564
	normal digestive/alimentary phenotype	J:311564
P2rx4^tm1Ando/P2rx4^tm1Ando Not Specified	abnormal blood vessel physiology	J:104459
	abnormal common carotid artery morphology	J:104459
	abnormal nitric oxide homeostasis	J:104459
	abnormal vascular endothelial cell physiology	J:104459
	abnormal vasodilation	J:104459
	decreased urine nitrite level	J:104459
	increased mean systemic arterial blood pressure	J:104459
P2rx4^{tm1b(EUCOMM)Wtsi}/P2rx4^{tm1b(EUCOMM)Wtsi} C57BL/6N-P2rx4^{tm1b(EUCOMM)Wtsi}/H	abnormal clavicle morphology	J:211773
	decreased mean corpuscular volume	J:211773
P2rx4^tm1Dgen/P2rx4^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	abnormal macrophage physiology	J:145232
P2rx4^tm1Rass/P2rx4^tm1Rass B6.Cg-P2rx4^tm1Rass	reduced long-term potentiation	J:112177

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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