P2rx4^tm1Rass
Targeted Allele Detail

Summary

• Symbol: P2rx4^tm1Rass
• Name: purinergic receptor P2X, ligand-gated ion channel 4; targeted mutation 1, Francois Rassendren PhD
• MGI ID: MGI:3665297
• Synonyms: P2rx4^tm1Rano, P2X4^-
• Gene: P2rx4 Location: Chr5:122845607-122867801 bp, + strand Genetic Position: Chr5, 62.53 cM
• Alliance: P2rx4^tm1Rass page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112177
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1, including the ATG, and part of intron 1 was replaced by a lacZ cassette. Western blot confirmed absence of protein in mutant brain, lung and submandibular gland samples. (J:112177)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any P2rx4 Mutation: 26 strains or lines available

References

• Original: J:112177 Sim JA, et al., Altered hippocampal synaptic potentiation in P2X4 knock-out mice. J Neurosci. 2006 Aug 30;26(35):9006-9
• All: 27 reference(s)