Shcbp1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Shcbp1
Shc SH2-domain binding protein 1
MGI:1338802

7 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
\Rag1^tm1(cre)Thr/? \Shcbp1^{tm1c(EUCOMM)Wtsi}/\Shcbp1^{tm1c(EUCOMM)Wtsi} involves: C57BL/6N	normal immune system phenotype	J:212898
\Shcbp1^{tm1c(EUCOMM)Wtsi}/\Shcbp1^{tm1c(EUCOMM)Wtsi} B6(Cg)-Shcbp1^{tm1c(EUCOMM)Wtsi}/Ravi	no abnormal phenotype detected	J:212898
\Shcbp1^{tm1c(EUCOMM)Wtsi}/\Shcbp1^{tm1c(EUCOMM)Wtsi} \Tg(Lck-cre)1Cwi/? involves: C57BL/6 * DBA/2	decreased susceptibility to experimental autoimmune encephalomyelitis	J:212898
	normal immune system phenotype	J:212898
\Shcbp1^{tm1d(EUCOMM)Wtsi}/\Shcbp1^{tm1d(EUCOMM)Wtsi} involves: C57BL/6N * FVB/N	decreased B cell number	J:212898
	decreased CD4-positive, alpha-beta T cell number	J:212898
	decreased macrophage cell number	J:212898
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:212898
	decreased T cell number	J:212898
	normal immune system phenotype	J:212898

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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