Fhl2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fhl2
four and a half LIM domains 2
MGI:1338762

19 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fhl2^em1Huag/Fhl2^em1Huag C57BL/6J-Fhl2^em1Huag	abnormal granulosa cell morphology	J:360852
	abnormal ovarian follicle number	J:360852
	decreased granulosa cell proliferation	J:360852
	decreased litter size	J:360852
	decreased secondary ovarian follicle number	J:360852
	decreased tertiary ovarian follicle number	J:360852
	impaired ovarian folliculogenesis	J:360852
	increased atretic ovarian follicle number	J:360852
	increased granulosa cell apoptosis	J:360852
	reduced female fertility	J:360852
	small ovary	J:360852
Fhl2^tm1Chen/Fhl2⁺ involves: 129S1/Sv * 129X1/SvJ	cardiac fibrosis	J:196433
Fhl2^tm1Chen/Fhl2⁺ involves: 129S1/Sv * 129X1/SvJ	cardiac hypertrophy	J:196433
Fhl2^tm1Chen/Fhl2^tm1Chen involves: 129S1/Sv * 129X1/SvJ * Black Swiss	no abnormal phenotype detected	J:64807
Fhl2^tm2Wlm/Fhl2^tm2Wlm B6.Cg-Fhl2^tm2Wlm	decreased bone mass	J:100765
	decreased bone mineral density	J:100765
	osteoporosis	J:100765
Fhl2^tm2Wlm/Fhl2^tm2Wlm Not Specified	cardiac hypertrophy	J:100289
Tg(Acp5-Fhl2)#Rosc/0 FVB/N-Tg(Acp5-Fhl2)#Rosc	normal skeleton phenotype	J:100765
Tg(Bglap2-Fhl2)#Rosc/0 FVB/N-Tg(Bglap2-Fhl2)#Rosc	increased bone mass	J:100765

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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