Hivep2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hivep2
human immunodeficiency virus type I enhancer binding protein 2
MGI:1338076

32 phenotypes from 1 allele in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hivep2^tm1Sis/Hivep2⁺ involves: BALB/cA * C57BL/6NCrlj * CBA/JNCrlj	decreased CD8-positive, alpha-beta T cell number	J:72249
	decreased single-positive T cell number	J:72249
Hivep2^tm1Sis/Hivep2^tm1Sis C.Cg-Hivep2^tm1Sis	abnormal T-helper 2 cell morphology	J:96024
Hivep2^tm1Sis/Hivep2^tm1Sis either: (involves: BALB/cA * C57BL/6NCrlj * CBA/JNCrlj) or (involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj)	abnormal astrocyte physiology	J:263351
	abnormal brain wave pattern	J:263351
	abnormal cerebellar granule cell morphology	J:263351
	abnormal cerebral cortex morphology	J:263351
	abnormal dentate gyrus morphology	J:263351
	abnormal nest building behavior	J:263351
	abnormal response to social novelty	J:263351
	abnormal spatial working memory	J:263351
	abnormal synaptic transmission	J:263351
	abnormal visual cortex morphology	J:263351
	anhedonia	J:263351
	CNS inflammation	J:263351
	decreased body weight	J:263351
	decreased neuron number	J:263351
	decreased oligodendrocyte number	J:263351
	decreased prepulse inhibition	J:263351
	hyperactivity	J:263351
	increased thermal nociceptive threshold	J:263351
	thin cerebral cortex	J:263351
Hivep2^tm1Sis/Hivep2^tm1Sis involves: BALB/cA * C57BL/6NCrlj * CBA/JNCrlj	abnormal immune system cell morphology	J:72249
	abnormal thymus cortex morphology	J:72249
	abnormal thymus lobule morphology	J:72249
	abnormal thymus medulla morphology	J:72249
	decreased single-positive T cell number	J:72249
	enlarged thymus cortex	J:72249
Hivep2^tm1Sis/Hivep2^tm1Sis involves: C57BL/6NCrlj * CBA/JNCrlj	abnormal dendritic spine morphology	J:271912
	abnormal dentate gyrus morphology	J:271912
	abnormal dentate gyrus neuron dendrite morphology	J:271912
	abnormal hippocampus granule cell morphology	J:271912
	increased dendritic spine length	J:271912
	increased locomotor activity	J:234969

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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