Ncr1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ncr1
natural cytotoxicity triggering receptor 1
MGI:1336212

15 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ncr1^noe/Ncr1^noe involves: C57BL/6J	abnormal NK cell physiology	J:179728
	decreased CD4-positive, alpha-beta T cell number	J:179728
	decreased CD8-positive, alpha-beta memory T cell number	J:179728
	decreased CD8-positive, alpha-beta T cell number	J:179728
	decreased susceptibility to Herpesvirales infection	J:179728
	decreased susceptibility to Herpesvirales infection induced morbidity/mortality	J:179728
	increased NK cell number	J:179728
	increased susceptibility to bacterial infection	J:179728
Ncr1^{tm1.1(icre)Viv}/Ncr1⁺ involves: C57BL/6	normal hematopoietic system phenotype	J:180265
Ncr1^{tm1.1(icre)Viv}/Ncr1⁺ involves: C57BL/6	no abnormal phenotype detected	J:180265
Ncr1^{tm1.1(icre)Viv}/Ncr1^{tm1.1(icre)Viv} involves: C57BL/6	abnormal NK cell physiology	J:179728
	decreased susceptibility to Herpesvirales infection induced morbidity/mortality	J:179728
	decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	J:179728
Ncr1^tm1Oman/Ncr1^tm1Oman involves: 129S1/Sv * 129X1/SvJ	decreased NK cell number	J:112394
	impaired natural killer cell mediated cytotoxicity	J:112394
	increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	J:112394
Ncr1^tm2.1Viv/Ncr1⁺ involves: C57BL/6	normal immune system phenotype	J:186000

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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