Bub1b Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bub1b
BUB1B, mitotic checkpoint serine/threonine kinase
MGI:1333889

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bub1b^tm1Jvd/Bub1b^tm1Jvd Mad2l1bp^tm1.1Itl/Mad2l1bp^tm1.1Itl Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129S6/SvEvTac * C57BL/6 * FVB	abnormal hepatocyte morphology	J:234643
	decreased body weight	J:234643
	hypoglycemia	J:234643
	improved glucose tolerance	J:234643
	increased hepatocyte karyomegaly	J:234643
	increased insulin sensitivity	J:234643
	polyploidy	J:234643
	postnatal growth retardation	J:234643
	preweaning lethality, incomplete penetrance	J:234643

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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