Mapkapk5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mapkapk5
MAP kinase-activated protein kinase 5
MGI:1333110

5 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mapkapk5^{tm1b(EUCOMM)Wtsi}/Mapkapk5^{tm1b(EUCOMM)Wtsi} C57BL/6N-Mapkapk5^{tm1b(EUCOMM)Wtsi}/Ieg	preweaning lethality, incomplete penetrance	J:211773
Mapkapk5^tm1Mgl/Mapkapk5^tm1Mgl involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:86268
Mapkapk5^tm1Pqs/Mapkapk5⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	delayed cellular replicative senescence	J:117893
	increased skin papilloma incidence	J:117893
Mapkapk5^tm1Pqs/Mapkapk5^tm1Pqs involves: 129S1/Sv * 129X1/SvJ * C57BL/6	delayed cellular replicative senescence	J:117893
	increased skin papilloma incidence	J:117893
	premature death	J:117893

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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