Pkp1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pkp1
plakophilin 1
MGI:1328359

19 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Pkp1^{tm2d(KOMP)Wtsi}/Pkp1^{tm2d(KOMP)Wtsi} involves: C57BL/6J * C57BL/6N * SJL/J	abnormal cell adhesion	J:233599
	abnormal corneocyte morphology	J:233599
	abnormal epidermis stratum corneum morphology	J:233599
	abnormal epidermis stratum granulosum morphology	J:233599
	abnormal epidermis suprabasal layer morphology	J:233599
	abnormal keratinocyte morphology	J:233599
	abnormal keratinocyte physiology	J:233599
	absent vibrissae	J:233599
	decreased birth weight	J:233599
	decreased keratinocyte proliferation	J:233599
	decreased skin tensile strength	J:233599
	decreased subcutaneous adipose tissue amount	J:233599
	dehydration	J:233599
	impaired skin barrier function	J:233599
	neonatal lethality, complete penetrance	J:233599
	skin lesions	J:233599
	thin epidermis stratum granulosum	J:233599
	thin skin	J:233599
	weight loss	J:233599

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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