Hipk3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hipk3
homeodomain interacting protein kinase 3
MGI:1314882

18 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hipk3^{Gt(OST51087)Lex}/Hipk3^{Gt(OST51087)Lex} involves: 129S5/SvEvBrd	abnormal pancreatic beta cell physiology	J:194563
	abnormal pancreatic islet morphology	J:194563
	decreased insulin secretion	J:194563
	decreased pancreatic beta cell proliferation	J:194563
	normal homeostasis/metabolism phenotype	J:194563
	impaired glucose tolerance	J:194563
	small pancreatic islets	J:194563
Hipk3^{tm1b(EUCOMM)Hmgu}/Hipk3^{tm1b(EUCOMM)Hmgu} C57BL/6N-Hipk3^{tm1b(EUCOMM)Hmgu}/Ieg	abnormal auditory brainstem response	J:211773
	decreased heart rate	J:211773
	decreased locomotor activity	J:211773
	decreased prepulse inhibition	J:211773
	decreased startle reflex	J:211773
	increased circulating alanine transaminase level	J:211773
	increased fasting circulating glucose level	J:211773
	increased heart rate variability	J:211773
	increased mean platelet volume	J:211773
	prolonged RR interval	J:211773
	thrombocytosis	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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