Hipk2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hipk2
homeodomain interacting protein kinase 2
MGI:1314872

29 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hipk2^tm1Afus/Hipk2^tm1Afus involves: 129X1/SvJ * C57BL/6	abnormal cell cycle	J:156574
	abnormal motor capabilities/coordination/movement	J:156574
	decreased birth weight	J:156574
	decreased body weight	J:156574
	decreased cell proliferation	J:156574
	limb grasping	J:156574
Hipk2^tm1Ejh/Hipk2^tm1Ejh involves: 129X1/SvJ * C57BL/6	abnormal gait	J:117465
	abnormal response to novelty	J:117465
	abnormal voluntary movement	J:117465
	decreased dopamine level	J:117465
	decreased dopaminergic neuron number	J:117465
	decreased exploration in new environment	J:117465
	decreased neuron apoptosis	J:117465
	decreased substantia nigra size	J:117465
	decreased tegmentum size	J:117465
	dystonia	J:117465
	impaired behavioral response to addictive substance	J:117465
	impaired coordination	J:117465
	limb grasping	J:117465
	short stride length	J:117465
Hipk2^tm1Ejh/Hipk2^tm1Ejh involves: 129X1/SvJ * C57BL/6J	enlarged trigeminal ganglion	J:93311
Hipk2^tm1Hko/Hipk2^tm1Hko involves: C57BL/6	abnormal neural tube morphology	J:106931
Hipk2^tm1Hko/Hipk2^tm1Hko involves: C57BL/6	decreased cellular sensitivity to ultraviolet irradiation	J:106931
Hipk2^{tm2b(EUCOMM)Hmgu}/Hipk2⁺ C57BL/6N-Hipk2^{tm2b(EUCOMM)Hmgu}/Cnrm	increased heart weight	J:211773
	increased kidney weight	J:211773
Hipk2^{tm2b(EUCOMM)Hmgu}/Hipk2^{tm2b(EUCOMM)Hmgu} C57BL/6N-Hipk2^{tm2b(EUCOMM)Hmgu}/Cnrm	abnormal lens morphology	J:211773
	abnormal maxilla morphology	J:211773
	abnormal snout morphology	J:211773
	abnormal tooth morphology	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23