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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Vamp2
vesicle-associated membrane protein 2
MGI:1313277
11 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Snap91tm1.1Tmar/\Snap91+
\Vamp2tm1Sud/\Vamp2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac 		abnormal CNS synaptic transmission J:228428
decreased anxiety-related response J:228428
decreased body weight J:228428
enhanced paired-pulse facilitation J:228428
postnatal growth retardation J:228428
\Snap91tm1.1Tmar/\Snap91tm1.1Tmar
\Vamp2tm1Sud/\Vamp2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac 		neonatal lethality, incomplete penetrance J:228428
postnatal lethality, complete penetrance J:228428
prenatal lethality, incomplete penetrance J:228428
\Vamp2tm1Sud/\Vamp2+
\Vamp3tm1Jpes/\Vamp3tm1Jpes
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J 		normal hematopoietic system phenotype J:121010
\Vamp2tm1Sud/\Vamp2tm1Sud
\Vamp3tm1Jpes/\Vamp3tm1Jpes
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		abnormal neurotransmitter secretion J:109985
decreased miniature excitatory postsynaptic current frequency J:109985
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory