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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Vamp2
vesicle-associated membrane protein 2
MGI:1313277
17 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Vamp2rlss/Vamp2rlss
involves: BALB/c * C3H/HeH * C57BL/6J 		abnormal motor capabilities/coordination/movement J:234901
abnormal sleep duration J:234901
Vamp2tm1(cre/ERT)Nat/Vamp2+
involves: 129 * C57BL/6 		no abnormal phenotype detected J:144315
Vamp2tm1(cre/ERT)Nat/Vamp2tm1(cre/ERT)Nat
involves: 129 * C57BL/6 		postnatal lethality J:144315
Vamp2tm1.1Jret/Vamp2tm1.1Jret
B6.129-Vamp2tm1.1Jret 		no abnormal phenotype detected J:205753
Vamp2tm1Sud/Vamp2+
involves: 129P2/OlaHsd * C57BL/6 		abnormal CNS synaptic transmission J:228428
abnormal excitatory postsynaptic potential J:228428
decreased anxiety-related response J:228428
decreased body weight J:228428
enhanced paired-pulse facilitation J:228428
postnatal growth retardation J:228428
Vamp2tm1Sud/Vamp2+
involves: 129P2/OlaHsd * C57BL/6J 		normal hematopoietic system phenotype J:121010
Vamp2tm1Sud/Vamp2tm1Sud
involves: 129P2/OlaHsd 		abnormal adrenal chromaffin cell morphology J:138035
Vamp2tm1Sud/Vamp2tm1Sud
involves: 129P2/OlaHsd * C57BL/6 		abnormal miniature excitatory postsynaptic currents J:72714
abnormal postnatal growth/weight/body size J:72714
decreased neurotransmitter release J:72714
normal immune system phenotype J:131926
neonatal lethality, complete penetrance J:72714
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory