Sart1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sart1
squamous cell carcinoma antigen recognized by T cells 1
MGI:1309453

24 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sart1^{Gt(IST11321E11)Tigm}/Sart1⁺ involves: C57BL/6N	abnormal chemokine secretion	J:241191
	abnormal hepatocyte physiology	J:241191
	abnormal immune cell physiology	J:241191
	abnormal Kupffer cell morphology	J:241191
	abnormal liver physiology	J:241191
	decreased body size	J:241191
	enlarged liver	J:241191
	increased circulating alanine transaminase level	J:241191
	increased circulating alkaline phosphatase level	J:241191
	increased circulating aspartate transaminase level	J:241191
	increased hepatocellular carcinoma incidence	J:241191
	increased liver tumor incidence	J:241191
	increased liver weight	J:241191
	increased neutrophil cell number	J:241191
	liver fibrosis	J:241191
	liver inflammation	J:241191
	microvesicular hepatic steatosis	J:241191
	ruffled hair	J:241191
Sart1^{Gt(IST11321E11)Tigm}/Sart1^{Gt(IST11321E11)Tigm} involves: C57BL/6N	abnormal vascular development	J:241191
	decreased embryo size	J:241191
	embryonic lethality during organogenesis, complete penetrance	J:241191
Sart1^{tm1.1(KOMP)Vlcg}/Sart1⁺ C57BL/6N-Sart1^{tm1.1(KOMP)Vlcg}/J	abnormal behavior	J:211773
	decreased thigmotaxis	J:211773
Sart1^{tm1.1(KOMP)Vlcg}/Sart1^{tm1.1(KOMP)Vlcg} C57BL/6N-Sart1^{tm1.1(KOMP)Vlcg}/J	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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