Sucla2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sucla2
succinate-Coenzyme A ligase, ADP-forming, beta subunit
MGI:1306775

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sucla2^{Gt(IST10208H1)Tigm}/Sucla2⁺ involves: 129S/SvEv * C57BL/6N	abnormal mitochondrial physiology	J:241325
	abnormal oxidative phosphorylation	J:241325
	normal cellular phenotype	J:241325
	decreased hepatocyte mitochondrial DNA content	J:241325
	decreased mitochondrial DNA content	J:241325
	decreased myocardial fiber mitochondrial DNA content	J:241325
	increased circulating carnitine level	J:241325
Sucla2^{Gt(IST10208H1)Tigm}/Sucla2^{Gt(IST10208H1)Tigm} involves: 129S/SvEv * C57BL/6N	prenatal lethality	J:241325
Sucla2^{Gt(SAbetageo)1Bhg}/Sucla2⁺ involves: 129S6/SvEvTac * C57BL/6	increased mitochondrial DNA content	J:213453
Sucla2^{Gt(SAbetageo)1Bhg}/Sucla2^{Gt(SAbetageo)1Bhg} involves: 129S6/SvEvTac * C57BL/6	abnormal mitochondrial morphology	J:213453
	abnormal mitochondrial physiology	J:213453
	abnormal placenta morphology	J:213453
	decreased fetal size	J:213453
	decreased mitochondrial DNA content	J:213453
	increased mitochondrial DNA content	J:213453
	perinatal lethality, complete penetrance	J:213453

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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