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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		E2f7
E2F transcription factor 7
MGI:1289147
24 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
E2f3tm2.1Gle/E2f3tm2.1Gle
E2f7tm1.1Gle/E2f7tm1.1Gle
E2f8tm1.1Gle/E2f8tm1.1Gle
involves: 129S6/SvEvTac 		normal embryo phenotype J:183999
E2f7tm1.1Gle/E2f7+
E2f8tm1.1Gle/E2f8tm1.1Gle
involves: 129S6/SvEvTac * FVB/N 		no abnormal phenotype detected J:131292
E2f7tm1.1Gle/E2f7tm1.1Gle
E2f8tm1.1Gle/E2f8+
involves: 129S6/SvEvTac * FVB/N 		decreased body size J:131292
premature death J:131292
E2f7tm1.1Gle/E2f7tm1.1Gle
E2f8tm1.1Gle/E2f8tm1.1Gle
involves: 129S6/SvEvTac 		abnormal embryo development J:183999
abnormal placenta development J:183999
abnormal placental labyrinth vasculature morphology J:183999
abnormal spongiotrophoblast cell morphology J:183999
abnormal trophoblast layer morphology J:183999
embryonic lethality during organogenesis, complete penetrance J:183999
fetal growth retardation J:183999
increased placenta apoptosis J:183999
small placenta J:183999
E2f7tm1.1Gle/E2f7tm1.1Gle
E2f8tm1.1Gle/E2f8tm1.1Gle
involves: 129S6/SvEvTac * FVB/N 		abnormal blood vessel morphology J:131292
abnormal vitelline vasculature morphology J:131292
decreased embryo size J:131292
embryonic lethality during organogenesis, complete penetrance J:131292
hemorrhage J:131292
increased embryonic tissue cell apoptosis J:131292
E2f7tm1Gle/E2f7tm1Gle
E2f8tm1Gle/E2f8tm1Gle
involves: 129S6/SvEvTac * FVB/N 		increased cellular sensitivity to alkylating agents J:131292
E2f7tm1Gle/E2f7tm1Gle
E2f8tm1Gle/E2f8tm1Gle
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * SJL 		abnormal embryonic tissue morphology J:183999
abnormal respiratory system morphology J:183999
normal embryo phenotype J:183999
neonatal lethality J:183999
E2f7tm1Gle/E2f7tm1Gle
E2f8tm1Gle/E2f8tm1Gle
Prl2c2tm1(cre)Gle/Prl2c2+
involves: 129S6/SvEvTac 		no abnormal phenotype detected J:183999
E2f7tm1Gle/E2f7tm1Gle
E2f8tm1Gle/E2f8tm1Gle
Prl3d1tm1(cre)Gle/Prl3d1+
involves: 129S6/SvEvTac 		no abnormal phenotype detected J:183999
E2f7tm1Gle/E2f7tm1Gle
E2f8tm1Gle/E2f8tm1Gle
Tg(Cyp19a1-cre)5912Gle/0
involves: 129S6/SvEvTac * FVB/N 		abnormal embryonic tissue morphology J:183999
abnormal placenta morphology J:183999
embryonic growth retardation J:183999
embryonic lethality during organogenesis, complete penetrance J:183999
hemorrhage J:183999
E2f7tm1Gle/E2f7tm1Gle
E2f8tm1Gle/E2f8tm1Gle
Tg(Tpbpa-cre,-EGFP)5Jcc/0
involves: 129S6/SvEvTac 		no abnormal phenotype detected J:183999
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory