Kcnn4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
MGI:1277957

45 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kcnn4^{em1(IMPC)Ccpcz}/Kcnn4^{em1(IMPC)Ccpcz} C57BL/6NCrl-Kcnn4^{em1(IMPC)Ccpcz}/Ccpcz	abnormal colon morphology	J:211773
	abnormal heart morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal rectum morphology	J:211773
	abnormal seminal vesicle morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal thymus morphology	J:211773
	abnormal tooth morphology	J:211773
	decreased erythrocyte cell number	J:211773
	decreased exploration in new environment	J:211773
	enlarged cecum	J:211773
	enlarged spleen	J:211773
	enlarged testis	J:211773
	enlarged thymus	J:211773
	hydrometra	J:211773
	increased fasting circulating glucose level	J:211773
	increased freezing behavior	J:211773
	increased red blood cell distribution width	J:211773
	increased spleen weight	J:211773
	small heart	J:211773
	small liver	J:211773
	small seminal vesicle	J:211773
	small thymus	J:211773
Kcnn4^tm1.1Jele/Kcnn4^tm1.1Jele either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	abnormal digestive system physiology	J:135743
Kcnn4^tm1Jemn/Kcnn4^tm1Jemn involves: 129S1/Sv * C57BL/6J	abnormal hematopoietic system physiology	J:94478
	abnormal T cell physiology	J:94478
	increased parotid gland size	J:94478
Kcnn4^tm1Rklr/Kcnn4^tm1Rklr B6.129S-Kcnn4^tm1Rklr	decreased susceptibility to injury	J:151989
Kcnn4^tm1Rklr/Kcnn4^tm1Rklr B6.129S-Kcnn4^tm1Rklr	renal interstitial fibrosis	J:151989
Kcnn4^tm1Rklr/Kcnn4^tm1Rklr involves: 129S/SvEv * C57BL/6	abnormal heart left ventricle morphology	J:124858
	abnormal heart morphology	J:124858
	abnormal red blood cell deformability	J:148910
	abnormal systemic arterial blood pressure	J:124858
	decreased vasodilation	J:124858
	enlarged spleen	J:148910
	increased erythrocyte osmotic fragility	J:148910
	increased heart weight	J:124858
	increased hematocrit	J:148910
	increased hemoglobin concentration distribution width	J:148910
	increased mean corpuscular volume	J:148910
	increased mean systemic arterial blood pressure	J:124858
	increased spleen iron level	J:148910
	increased spleen weight	J:148910
	increased systemic arterial diastolic blood pressure	J:124858
	increased systemic arterial systolic blood pressure	J:124858
	macrocytosis	J:148910

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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